About 1 in 8 men will be diagnosed with prostate cancer during his lifetime.

The prostate is a small, walnut-shaped gland that is part of the male reproductive system. Located below the bladder and in front of the rectum, it surrounds the urethra—the tube that carries urine from the bladder through the penis. The prostate’s primary role is to produce fluid that helps nourish and transport sperm as part of semen. Prostate cancer is one of the most common cancers in men and typically develops in the cells responsible for producing and releasing fluids. In many cases, prostate cancer grows slowly and remains confined to the prostate, though some forms can be more aggressive and spread more quickly. While the exact cause of prostate cancer is not known, several factors can increase a man’s risk, including advancing age, a family history of prostate or breast cancer, obesity, and race or ethnicity, with Black men having a significantly higher risk of developing the disease.

Adrenal tumors are found in about 1 in every 10 people who have an imaging test (like a CT or MRI) of the adrenal gland. Most are benign adenomas.

Adrenal cancer is a rare condition that develops in the adrenal glands, which are small, triangle-shaped glands located on top of the kidneys and responsible for producing hormones that affect nearly every organ and tissue in the body. Cancerous tumors of the adrenal gland are known as adrenal cortical carcinomas, while noncancerous growths are called benign adenomas. Benign adenomas typically occur in only one adrenal gland and often do not cause symptoms. In contrast, adrenal cortical carcinomas may grow large enough to press on surrounding organs and can produce excess hormones, leading to noticeable symptoms. Although adrenal cancer can occur at any age, it is most commonly diagnosed in children under five and in adults in their 40s and 50s.

Bladder cancer accounts for about 7% of all new cancers in the U.S.

The bladder is a hollow, balloon-shaped organ in the pelvis that stores urine. Bladder cancer occurs when abnormal cells develop in the bladder, most often starting in the cells that line its inner surface. These cells can mutate and grow uncontrollably, forming a tumor. Bladder cancer is most commonly diagnosed in individuals over the age of 55 and occurs more frequently in men.

Kidney cancer is among the 10 most common cancers in both men and women. Overall, the lifetime risk for developing kidney cancer is about 1 in 63.

The kidneys are two bean-shaped organs, each about the size of a fist, that filter waste and excess fluid from the blood to produce urine. Kidney cancer, also called renal cancer, develops when abnormal cells grow in one or both kidneys. The most common type begins in the lining of the kidney’s small filtering tubes, known as renal cell carcinoma.

About 1 in every 263 males will develop testicular cancer at some point during his life.

The testicles (testes) are oval-shaped organs located in the scrotum, the pouch of skin beneath the penis. They are responsible for producing sperm and male sex hormones. Testicular cancer develops when abnormal cells form in one testicle, which is where it is most often found. Although relatively rare overall, testicular cancer is the most common cancer diagnosed in American males between the ages of 15 and 35.